Successful Cognitive Aging: Between Functional Decline and Failure of Compensatory Mechanisms.

نویسندگان

  • Marc Verny
  • Emmanuel Moyse
  • Slavica Krantic
چکیده

1APHP, DHU FAST, Groupe Hospitalier Pitié Salpêtrière-Charles Foix, Centre de Gériatrie, Pierre & Marie University, Sorbonne-Paris-Cité Universities, UMR 8256 CNRS B2A, 47-83 boulevard de l’Hôpital, 75013 Paris, France 2INRA Centre, Physiology and Behavior Unit, University François Rabelais of Tours, 37380 Nouzilly, France 3Centre de Recherche des Cordeliers, Paris-Descartes University, Sorbonne-Paris-Cité, Pierre and Marie Curie University, UMR-S-1138 INSERM, 15 rue de l’École de Médecine, 75006 Paris, France

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Age-related functional reorganization, structural changes, and preserved cognition

Although healthy aging is associated with general cognitive decline, there is considerable variability in the extent to which cognitive functions decline or are preserved. Preserved cognitive function in the context of age-related neuroanatomical and functional changes, has been attributed to compensatory mechanisms. However, the existing sparse evidence is largely focused on functions associat...

متن کامل

Attempted and Successful Compensation in Preclinical and Early Manifest Neurodegeneration – A Review of Task fMRI Studies

Several models of neural compensation in healthy aging have been suggested to explain brain activity that aids to sustain cognitive function. Applying recently suggested criteria of "attempted" and "successful" compensation, we reviewed existing literature on compensatory mechanisms in preclinical Huntington's disease (HD) and amnestic mild cognitive impairment (aMCI). Both disorders constitute...

متن کامل

Review of Mechanisms and Theories of Aging

Several factors have incentive role for study of aging which includes increasing of the average and maximum of human life span, the increase in percentage of elderly in the societies and proportion of the national expenditure utilized by them. The Recent views of aging indicating that aging is extremely a complex multifactorial process despite of earlier views about definite cause aging like ge...

متن کامل

Dynamic Functional Reorganizations and Relationship with Working Memory Performance in Healthy Aging

In recent years, several theories have been proposed in attempts to identify the neural mechanisms underlying successful cognitive aging. Old subjects show increased neural activity during the performance of tasks, mainly in prefrontal areas, which is interpreted as a compensatory mechanism linked to functional brain efficiency. Moreover, resting-state studies have concluded that elders show di...

متن کامل

Reconnecting cognition in the lab and cognition in real life: The role of compensatory social and motivational factors in explaining how cognition ages in the wild.

The papers in this Special Issue compellingly show that older adults' everyday cognitive life is governed not by the decline in elementary cognitive processes as measured in the lab, but by a multitude of compensatory mechanisms, most of which are of the social/motivational variety. Much of this compensatory behavior can be elicited with no or only little experimental prodding, underscoring the...

متن کامل

ذخیره در منابع من

ذخیره در منابع من قبلا به منابع من ذحیره شده

{@ msg_add @}


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • BioMed research international

دوره 2015  شماره 

صفحات  -

تاریخ انتشار 2015